abstract：OBJECTIVE:To define embarrassment and develop an understanding of the role of embarrassment in relation to cervical cancer screening and self-collected human papillomavirus (HPV) DNA testing in Uganda. DESIGN:Cross-sectional, qualitative study using semistructured one-to-one interviews and focus groups. PARTICIPANTS:...

journal_title：BMJ open

authors： Teng FF,Mitchell SM,Sekikubo M,Biryabarema C,Byamugisha JK,Steinberg M,Money DM,Ogilvie GS

更新日期：2014-04-11 00:00:00

abstract：BACKGROUND:The UK has the highest rate of teenage pregnancies in Western Europe, a fifth are repeat pregnancies. Unintended conceptions can result in emotional, psychological and educational harm to teenage girls, often with enduring implications for their life chances. Babies of teenage mothers have increased mortalit...

journal_title：BMJ open

authors： Whitaker R,Hendry M,Booth A,Carter B,Charles J,Craine N,Edwards RT,Lyons M,Noyes J,Pasterfield D,Rycroft-Malone J,Williams N

更新日期：2014-04-10 00:00:00

abstract：OBJECTIVE:To investigate whether there is a difference in the treatment effect of donepezil on cognition in Alzheimer disease between industry-funded and independent randomised controlled trials. DESIGN:Fixed effects meta-analysis of standardised effects of donepezil on cognition as measured by the Mini Mental State E...

journal_title：BMJ open

authors： Killin LO,Russ TC,Starr JM,Abrahams S,Della Sala S

更新日期：2014-04-07 00:00:00

abstract：OBJECTIVES:CT colonography (CTC) may be an acceptable test for colorectal cancer screening but bowel preparation can be a barrier to uptake. This study tested the hypothesis that prospective screening invitees would prefer full-laxative preparation with higher sensitivity and specificity for polyps, despite greater bur...

journal_title：BMJ open

authors： Ghanouni A,Halligan S,Taylor SA,Boone D,Plumb A,Stoffel S,Morris S,Yao GL,Zhu S,Lilford R,Wardle J,von Wagner C

更新日期：2014-04-03 00:00:00

abstract：OBJECTIVE:Risk factors for breast, colorectal, and lung cancer are known to be more common among lesbian, gay, and bisexual (LGB) individuals, suggesting they may be more likely to develop these cancers. Our objective was to determine differences in cancer incidence by sexual orientation, using sexual orientation data ...

journal_title：BMJ open

authors： Boehmer U,Miao X,Maxwell NI,Ozonoff A

更新日期：2014-03-26 00:00:00

abstract：INTRODUCTION:'Take Home' Naloxone (THN) kits for use by peers in the event of an opioid overdose may reduce further overdose and deaths, but distribution through Drugs Services may not reach those at highest risk. Attendance by paramedics at emergency calls for patients who have suffered an overdose presents an opportu...

journal_title：BMJ open

authors： Moore C,Lloyd G,Oretti R,Russell I,Snooks H

更新日期：2014-03-20 00:00:00

abstract：BACKGROUND:The last two decades have seen an increase in literature reporting an increase in knowledge and use of contraceptives among individuals and couples in Kenya, as in the rest of Africa, but there is a dearth of information regarding knowledge about benefits of family planning (FP) in Kenya. OBJECTIVES:To asse...

journal_title：BMJ open

authors： Mutombo N,Bakibinga P,Mukiira C,Kamande E

更新日期：2014-03-18 00:00:00

abstract：OBJECTIVES:To compare the clinical, socioeconomic and demographic characteristics of individuals diagnosed with Neisseria gonorrhoeae (NG) in the community using a concomitant nucleic acid amplification test (NAAT, AptimaCombo2) as part of the (community-based) UK Chlamydia Screening Programme (CSP), with those diagnos...

journal_title：BMJ open

authors： Cook PA,Evans-Jones J,Mallinson H,Wood M,Alloba F,Jones K,Strodtbeck S,Hanna-Bashara L

更新日期：2014-03-14 00:00:00

abstract：BACKGROUND:The amount of scientific literature available is often overwhelming, making it difficult for researchers to have a good overview of the literature and to see relations between different developments. Visualisation techniques based on bibliometric data are helpful in obtaining an overview of the literature on...

journal_title：BMJ open

authors： Rodrigues SP,van Eck NJ,Waltman L,Jansen FW

更新日期：2014-03-13 00:00:00

abstract：OBJECTIVES:A central tenet of organised cancer screening is that all persons in a target population are invited. The aims of this study were to identify participant and physician factors associated with response to mailed physician-linked invitations (study 1) and to evaluate their effectiveness in an organised colorec...

journal_title：BMJ open

authors： Tinmouth J,Baxter NN,Paszat LF,Rabeneck L,Sutradhar R,Yun L

更新日期：2014-03-12 00:00:00

abstract：OBJECTIVES:We investigated associations of officially recorded crime and perceived neighbourhood safety with physical health, evaluating potential effect modification by gender. SETTING:Nationally representative population-based survey in New Zealand. PARTICIPANTS:Individual-level data from 6995 New Zealand General S...

journal_title：BMJ open

authors： Lovasi GS,Goh CE,Pearson AL,Breetzke G

更新日期：2014-03-10 00:00:00

abstract：OBJECTIVE:Maternal and child health (MCH) care may provide an entry point for HIV services in high HIV-prevalence settings. Our objective was to assess integration of HIV with MCH services in public sector facilities in Swaziland. DESIGN:In 2009, 2010 and 2012, client flow assessments (CFAs) were conducted over 5 days...

journal_title：BMJ open

authors： Birdthistle IJ,Mayhew SH,Kikuvi J,Zhou W,Church K,Warren CE,Nkambule R,Fenty J,Integra Initiative.

更新日期：2014-03-07 00:00:00

abstract：OBJECTIVE:To synthesise the available evidence and estimate the comparative efficacy of control strategies to prevent total hip replacement (THR)-related surgical site infections (SSIs) using a mixed treatment comparison. DESIGN:Systematic review and mixed treatment comparison. SETTING:Hospital and other healthcare s...

journal_title：BMJ open

authors： Zheng H,Barnett AG,Merollini K,Sutton A,Cooper N,Berendt T,Wilson J,Graves N

更新日期：2014-03-06 00:00:00

abstract：OBJECTIVE:To evaluate the impact of a model of rural community health service (CHS) on the use and acceptability of primary healthcare services. DESIGN:Quasi-experimental. SETTING:Two adjacent rural counties in China. PARTICIPANTS:5842 residents in 2009 and 3807 in 2010 from 980 households in 7 intervention township...

journal_title：BMJ open

authors： Liu Y,Yuan Z,Liu Y,Jayasinghe UW,Harris MF

更新日期：2014-02-28 00:00:00

abstract：OBJECTIVES:For characterisation of mineral bone disease in chronic kidney disease (CKD), laboratory surrogates have been suggested. This observational should investigate the association of total and skeletal alkaline phosphatase (AP) with mortality of patients undergoing maintenance renal replacement therapy. SETTING:...

journal_title：BMJ open

authors： Beige J,Wendt R,Girndt M,Queck KH,Fiedler R,Jehle P

更新日期：2014-02-27 00:00:00

abstract：OBJECTIVE:To examine whether confidence in primary healthcare (PHC) differs among ethnic-linguistic groups and which PHC experiences are associated with confidence. DESIGN:A cross-sectional study where patient surveys were administered using random digit dialling. Regression models identify whether ethnic-linguistic g...

journal_title：BMJ open

authors： Wong ST,Black C,Cutler F,Brooke R,Haggerty JL,Levesque JF

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:In 2002, the WHO declared interpersonal violence to be a leading public health problem. Previous research demonstrates that urban spaces with a high incidence of violent trauma (hotspots) correlate with features of built environment and social determinants. However, there are few studies that analyse injury ...

journal_title：BMJ open

authors： Walker BB,Schuurman N,Hameed SM

更新日期：2014-02-20 00:00:00

abstract：INTRODUCTION:Owing to the high and increasing morbidity and mortality, chronic obstructive pulmonary disease (COPD) has become a major public health problem worldwide. Although the majority of patients with COPD are in the early stages, little attention has been paid to them, in particular regarding to early interventi...

journal_title：BMJ open

authors： Li X,Zhou Y,Chen S,Zheng J,Zhong N,Ran P

更新日期：2014-02-18 00:00:00

abstract：OBJECTIVES:Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication ut...

journal_title：BMJ open

authors： Lupattelli A,Spigset O,Twigg MJ,Zagorodnikova K,Mårdby AC,Moretti ME,Drozd M,Panchaud A,Hämeen-Anttila K,Rieutord A,Gjergja Juraski R,Odalovic M,Kennedy D,Rudolf G,Juch H,Passier A,Björnsdóttir I,Nordeng H

更新日期：2014-02-17 00:00:00

abstract：INTRODUCTION:Many people residing in low-income and middle-income countries (LMICs) are regularly exposed to catastrophic healthcare expenditure. It is therefore pertinent that LMICs should finance their health systems in ways that ensure that their citizens can use needed healthcare services and are protected from pot...

journal_title：BMJ open

authors： Adebayo EF,Ataguba JE,Uthman OA,Okwundu CI,Lamont KT,Wiysonge CS

更新日期：2014-02-14 00:00:00

abstract：OBJECTIVES:To report on the causes of blindness certifications in England and Wales in working age adults (16-64 years) in 2009-2010; and to compare these with figures from 1999 to 2000. DESIGN:Analysis of the national database of blindness certificates of vision impairment (CVIs) received by the Certifications Office...

journal_title：BMJ open

authors： Liew G,Michaelides M,Bunce C

更新日期：2014-02-12 00:00:00

abstract：OBJECTIVE:To complete a systematic review of the literature describing associations between all environmental exposures and asthma symptoms and exacerbations in children up to mean age of 9 years. DESIGN:Systematic review. SETTING:Reference lists of identified studies and reviews were searched for all articles publis...

journal_title：BMJ open

authors： Dick S,Doust E,Cowie H,Ayres JG,Turner S

更新日期：2014-02-12 00:00:00

abstract：OBJECTIVES:The aim was to study whether a workplace-registered frequent short-term sick leave spell pattern was an early indicator of future disability pension or future long-term sick leave among municipal eldercare workers. SETTING:The municipal healthcare sector in the city of Aarhus, which is the second largest ci...

journal_title：BMJ open

authors： Stapelfeldt CM,Nielsen CV,Andersen NT,Krane L,Borg V,Fleten N,Jensen C

更新日期：2014-02-07 00:00:00

abstract：OBJECTIVE:To investigate how accurately doctors estimated their performance on the General Medical Council's Tests of Competence pilot examinations. DESIGN:A cross-sectional survey design using a questionnaire method. SETTING:University College London Medical School. PARTICIPANTS:524 medical doctors working in a ran...

journal_title：BMJ open

authors： Mehdizadeh L,Sturrock A,Myers G,Khatib Y,Dacre J

更新日期：2014-02-06 00:00:00

abstract：OBJECTIVES:This study aimed to investigate whether violent and non-violent offending were related to elevated risk of suicide. We also investigated whether the risk was higher among those with repeated offences and how experiences of substance misuse and suicide attempt modified the relationship. DESIGN:A nationwide p...

journal_title：BMJ open

authors： Stenbacka M,Romelsjö A,Jokinen J

更新日期：2014-02-03 00:00:00

abstract：OBJECTIVES:Atrial fibrillation (AF) is the most common cardiac rhythm disorder with a significant health burden. The aim of this study was to characterise patients with recently diagnosed AF and to estimate the rates of comorbidities and outcome events requiring hospitalisation in routine clinical practice. DESIGN:Pha...

journal_title：BMJ open

authors： Gallagher AM,van Staa TP,Murray-Thomas T,Schoof N,Clemens A,Ackermann D,Bartels DB

更新日期：2014-01-27 00:00:00

abstract：OBJECTIVES:The detailed course of mental disorders at the acute and subacute stages of mild traumatic brain injury (mTBI), especially with regard to recovery from sleep disturbances, has not been well characterised. The aim of this study was to determine the course of depression, anxiety and sleep disturbance, followin...

journal_title：BMJ open

authors： Ma HP,Ou JC,Yeh CT,Wu D,Tsai SH,Chiu WT,Hu CJ

更新日期：2014-01-23 00:00:00

abstract：OBJECTIVES:To test the effects of a school-based prevention programme on students' smoking-related behaviour, attitudes and knowledge 6 months after implementation over 2 school-years has ended. DESIGN:Two-arm prospective cluster randomised controlled trial with a follow-up survey 6 months after end of programme imple...

journal_title：BMJ open

authors： Isensee B,Hansen J,Maruska K,Hanewinkel R

更新日期：2014-01-21 00:00:00

abstract：OBJECTIVE:To investigate the risk of cancer and potential gender effects in persons hospitalised with burn injury. DESIGN:Population-based retrospective cohort study using record-linkage systems in Scotland and Western Australia. PARTICIPANTS:Records of 37 890 and 23 450 persons admitted with a burn injury in Scotlan...

journal_title：BMJ open

authors： Duke JM,Bauer J,Fear MW,Rea S,Wood FM,Boyd J

更新日期：2014-01-17 00:00:00

abstract：OBJECTIVE:Lean interventions aim to improve quality of healthcare by reducing waste and facilitate flow in work processes. There is conflicting evidence on the outcomes of lean thinking, with quantitative and qualitative studies often contradicting each other. We suggest that reviewing the literature within the approac...

journal_title：BMJ open

authors： Andersen H,Røvik KA,Ingebrigtsen T

更新日期：2014-01-15 00:00:00

abstract：OBJECTIVES:Apolipoprotein C3 (ApoC3) polymorphisms have been suggested to be associated with risk of coronary heart disease (CHD). However, the results of relevant studies were inconsistent. We aimed to systematically evaluate this issue. DESIGN:PubMed, EMBASE and Cochrane library databases (up to March 2013) were sys...

journal_title：BMJ open

authors： Lin B,Huang Y,Zhang M,Wang J,Wu Y

更新日期：2014-01-14 00:00:00

abstract：INTRODUCTION:In patients with large abdominal aortic aneurysm (AAA), open surgical or endovascular aneurysm repair procedures are often used to minimise the risk of aneurysm-related rupture and death; however, aneurysm repair itself carries a high risk. Low cardiopulmonary fitness is associated with an increased risk o...

journal_title：BMJ open

authors： Tew GA,Weston M,Kothmann E,Batterham AM,Gray J,Kerr K,Martin D,Nawaz S,Yates D,Danjoux G

更新日期：2014-01-10 00:00:00

abstract：OBJECTIVES:To compare the short-term and long-term effectiveness of human papillomavirus (HPV) tests in Norwegian Cervical Cancer Screening Programme (NCCSP). DESIGN:Nationwide register-based prospective follow-up study. SETTING:In 2005, the NCCSP implemented HPV testing in follow-up of unsatisfactory, atypical squam...

journal_title：BMJ open

authors： Nygård M,Røysland K,Campbell S,Dillner J

更新日期：2014-01-08 00:00:00

abstract：OBJECTIVE:Chronic obstructive pulmonary disease (COPD) is among the leading causes of morbidity and mortality worldwide, but longitudinal studies of the economic consequences of COPD are scarce. This Danish study evaluated for the first time ever the economic consequences of COPD of an entire nation before and after th...

journal_title：BMJ open

authors： Løkke A,Hilberg O,Tønnesen P,Ibsen R,Kjellberg J,Jennum P

更新日期：2014-01-06 00:00:00

abstract：OBJECTIVES:This study aimed to assess the association of socioeconomic conditions with female fertility impairment among women who delivered a live birth. DESIGN:Cross-sectional analysis. SETTING:Population-based birth cohort (Generation XXI) assembled in 2005/2006 from five public maternity units in Porto Metropolit...

journal_title：BMJ open

authors： Correia S,Rodrigues T,Barros H

更新日期：2014-01-02 00:00:00

abstract：OBJECTIVES:Chromosome 9p21 single nucleotide polymorphism (SNP) is a susceptibility variant for acute myocardial infarction (AMI) in the primary prevention setting. However, it is controversial whether this SNP is also associated with recurrent myocardial infarction (ReMI) in the secondary prevention setting. The purpo...

journal_title：BMJ open

authors： Hara M,Sakata Y,Nakatani D,Suna S,Usami M,Matsumoto S,Ozaki K,Nishino M,Sato H,Kitamura T,Nanto S,Hamasaki T,Tanaka T,Hori M,Komuro I,OACIS Investigators.

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Sarcoidosis is an incurable, chronic granulomatous disease primarily involving the lungs and lymph nodes of unknown aetiology, treated with non-specific anti-inflammatory/immunosuppressive drugs. Persistently symptomatic patients worsen with a disabling, potentially fatal clinical course. To determine a po...

journal_title：BMJ open

authors： Robinson LA,Smith P,Sengupta DJ,Prentice JL,Sandin RL

更新日期：2013-12-23 00:00:00

abstract：OBJECTIVES:To identify effective interventions to increase organ donor registration and improve knowledge about organ donation among ethnic minorities in North America and the UK. DESIGN:Systematic review. DATA SOURCES:MEDLINE, EMBASE, PsycINFO, CINAHL and Cochrane Central searched up to November 2012, together with ...

journal_title：BMJ open

authors： Deedat S,Kenten C,Morgan M

更新日期：2013-12-20 00:00:00

abstract：OBJECTIVE:To assess the effect that accreditation training in fetal growth surveillance and evidence-based protocols had on stillbirth rates in England and Wales. DESIGN:Analysis of mortality data from Office of National Statistics. SETTING:England and Wales, including three National Health Service (NHS) regions (Wes...

journal_title：BMJ open

authors： Gardosi J,Giddings S,Clifford S,Wood L,Francis A

更新日期：2013-12-17 00:00:00

abstract：OBJECTIVES:There has not previously been a systematic comparison of awards for research funding in infectious diseases by sex. We investigated funding awards to UK institutions for all infectious disease research from 1997 to 2010, across disease categories and along the research and development continuum. DESIGN:Syst...

journal_title：BMJ open

authors： Head MG,Fitchett JR,Cooke MK,Wurie FB,Atun R

更新日期：2013-12-09 00:00:00